Beginner Home exercise programme (Body weight)
March 24, 2020How to Analyze your Data in Performance Fingerprint
April 1, 2020
Use ASSIC Performance Fingerprint to upload and monitor your health parameters
Biology
- Most likely source of virus infection originated from transition from Pangolins to Humans and subsequent spread from human to human
- Infection can be spread by asymptomatic carriers
- Viral particles enter in lungs via droplet infection. Other modes of infection unclear
Epidemiology:
- Typical incubation time 4-14 days (up to 24 days)
- China notified WHO 31-12-2019
- WHO declared pandemic 11-03-2020
At risk:
- Congregations of people
- Areas of infections
Symptoms
- Cough (65-80%)
- Fever (45%)
- Shortness of breath (20-40%)
- Upper respiratory tract symptoms (15%)
- Gastrointestinal symptoms (10%)
Monitor relevant Vitals
- Temperature
- Heart rate and BP
- Respiratory rate
Laboratory investigations
- Decreased WCC and lymphopaenia
- Increase BUN/Cr
- LFTs: increase in AST/ALT/Tbil
- Increase D-dimer
- Increase CRP
- Increase LDH
- Decrease Procalcitonin (if secondary bacterial infection it will be elevated)
- PCR COVID-19 test
Chest X-ray
- Hazy bilateral peripheral opacities on chest X-ray
- CT scan: ground glass opacities, consolidation
Treatment
Prevention
- Prevent infection with necessary precautions
- Hand cleaning: 20+ seconds with soap and water or preferably alcohol based solution
- Isolate/Quarantine
Anti flu viral medication and anti retroviral medication being used. Treatment experimental presently. Guidelines to follow.
- Remdesivir: anti RNA polymerase
- Chloroquine: blocks virus entry into endosome
- Tocilizumab: block IL-6
Supportive treatment
- Avoid anti-inflammatory medication (NSAID)
- Respiratory failure management
- Adequate nutrition
- Prolonged bed rest: Deep Vein Thrombosis (DVT) exercise routine to prevent DVT and pulmonary embolism complications
Mortality associated with:
- Elderly
- Immunocompromised individulas: examples include HIV/Oncology patients
- Medical conditions: Diabetes, Chronic Obstructive Airways Disease
Laboratory predictors of poor outcome:
- Increase D dimer
- Increase ferritin
- Increase troponin
- Increase cardiac myoglobin
- Monitor secondary infection
Use ASSIC Performance Fingerprint to upload and monitor your health parameters
Precaution
- Glove protection
- N95 masks
- Hand hygiene:20 + seconds with soap and water or alcohol containing solution
